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InVivoGo! QVD : Pan Caspase Inhibitor (PDF)


Product Number Amount/Size Price
#A0004 500ul $540
#A0004 1000ul $1,080
#A0004 1500ul $1,620


Description

From the Discoverer’s of Q-VD-OPh1 and Q-VE-OPh2: Q-VD-OPh [Q-Val-Asp-OPh] is a next generation pan-caspase inhibitor.1,2 In Vivo Go! QVD is highly cell permeable, crosses the blood-brain barrier, and irreversibly inhibits caspase activity to prevent apoptosis. Q-VD-OPh is nontoxic and significantly more active than existing fluoromethylketone (-fmk) conjugates, which have been shown to be toxic.3


Applications

InVivoGo! QVD is specifically formulated for in vivo studies1-5. Q-VD-OPh is provided at a concentration of 10mg/ml to use 50ul/25g animal for a final dosage of 20mg/kg.


Stability and Storage Conditions:

Each lot is individually certified for Quality Control. Stable for 1 year. Store at 40C


References

1. Caserta TM, 2003. Apoptosis 8:345-352
2. Van Noorden CJ, 2001 Acta Histochem. 103:241-51
3. Renolleau S, 2007 J. Neurochem. 100:1062-71
4. Psotka MA, 2009 Infect. Immun. 77:959-969
5. Southerland B, 2010 J. Cell Death 3:33-40


Companion Products

Q-VE-OPh Apoptosis Negative Control (#A0007)
Caspase 9 Apoptosis Extracts (#E0009)
Caspase 3 Apoptosis Extracts (#E0003)
Caspase 8 Apoptosis Extracts (#E0008)
PARP Apoptosis Extracts (#S0001)
XIAP Apoptosis Extracts (#S0002)
BID Apoptosis Extracts (#S0003)
CHAPS Cell Extract Buffer (#B0001)
Caspase-Cleaved Anti-Beclin 1 antibody (Ab#00011)


For research purposes only. Not for use in humans.

Apoptrol, LLC
PO Box 32, Enon, OH 45323-0032
Phone: 937-623-8729